Table 2. Tissue weights at the time of sacrifice.

	IL 10tm 6 months Mean ± SEM n = 16	C57Bl/6 6 months Mean ± SEM n = 16	p-value	IL 10tm 12 months Mean ± SEM n = 21	C57Bl/6 12 months Mean ± SEM n = 14	p-value	IL 10tm 23 months Mean ± SEM n = 19	C57Bl/6 23 months Mean ± SEM n = 23	p-value
Body Weight	24.71 ± 0.51	22.60 ± 0.35	0.0019	33.62 ± 1.19	25.75 ± 0.65	< 0.0001	27.80 ± 0.70	32.14 ± 1.4	0.0135
Heart (% of BW)	0.577 ± 0.025	0.572 ± 0.022	0.9032	0.432 ± 0.017	0.488 ± 0.025	0.078	0.590 ± 0.028	0.539 ± 0.027	0.2010
Liver (%of BW)	5.107 ± 0.126	4.879 ± 0.146	0.2464	4.903 ± 0.153	4.873 ± 0.158	0.8938	6.511 ± 0.375	5.125 ± 0.261	0.0034
Kidney (% of BW)	1.531 ± 0.152	01.747 ± 0.144	0.3112	1.054 ± 0.036	1.289 ± 0.023	< 0.0001	1.507 ± 0.079	1.500 ± 0.072	0.9502
Brown Fat (% of BW)	0.335 ± 0.069	0.266 ± 0.021	0.3479	0.357 ± 0.017	0.363 ± 0.023	0.8129	0.303 ± 0.021	0.407 ± 0.027	0.0056
Visceral Fat (% of BW)	2.286 ± 0.271	1.564 ± 0.139	0.0244	3.446 ± 0.390	1.606 ± 0.211	0.0010	1.450 ± 0.353	2.723 ± 0.341	0.0159
Perinephric Fat (% of BW)	0.477 ± 0.021	0.394 ± 0.075	0.3076	0.779 ± 0.088	0.562 ± 0.144	0.1949	0.480 ± 0.120	1.210 ± 0.200	0.0094
Subcutaneous Fat (% of BW)	0.919 ± 0.047	0.782 ± 0.050	0.0565	2.074 ± 0.176	1.174 ± 0.110	0.0005	1.117 ± 0.296	2.134 ± 0.270	0.0166
Tibialis Anterior (% of BW)	0.353 ± 0.011	0.425 ± 0.014	0.0005	0.282 ± 0.008	0.355 ± 0.009	< 0.0001	0.244 ± 0.012	0.259 ± 0.010	0.3195
Quadriceps (% of BW)	1.271 ± 0.034	1.456 ± 0.015	< 0.0001	1.117 ± 0.027	1.389 ± 0.028	< 0.0001	0.860 ± 0.050	0.943 ± 0.037	0.1841
Gastroc- nemius (% of BW)	0.978 ± 0.026	1.123 ± 0.017	<0.0001	0.801 ± 0.021	0.963 ± 0.022	< 0.0001	0.725 ± 0.036	0.771 ± 0.028	0.3210
Extensor Digitorum Longus (% of BW)	0.092 ± 0.003	0.102 ± 0.007	0.2264	0.062 ± 0.003	0.073 ± 0.002	0.0082	0.047 ± 0.004	0.060 ± 0.003	0.0242
Triceps (% of BW)	0.771 ± 0.033	0.862 ± 0.034	0.0667	0.702 ± 0.018	0.837 ± 0.025	< 0.0001	0.530 ± 0.035	0.598 ± 0.029	0.9097
Soleus (% of BW)	0.068 ± 0.005	0.074 ± 0.005	0.2263	0.052 ± 0.003	0.064 ± 0.002	0.0098	0.044 ± 0.004	0.046 ± 0.003	0.6175

Weights of tissues dissected at time of sacrifice. SEM = Standard error of the mean