Table 4. The attractors of the Boolean model as depicted in Fig 1B obtained from the synchronous update method.
In each version of the model, the number of single SSs and the corresponding normalized basin of attractions are demonstrated. The color gradient from red, yellow to green illustrate the lowest to the highest values, respectively. A to K attractors are encoded in the following order: Activator/DNA/mRNA/Protein. The D*, H* and K* denote specific states pertaining to this Central Dogma modeling.
| Central Dogma 1965 | Description | No. SSs with one state | A | B | C | D* | E | F | G | H* | I | J | K* |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0000 | 1000 | 1001 | 0001 | 0100 | 1100 | 1111 | 0111 | 0110 | 1101 | 0101 | |||
| V1 | Activatory gene expression | 8 | 12.5 | 6.25 | 18.75 | 12.5 | 12.5 | 6.25 | 18.75 | 12.5 | - | - | - |
| V2 | Inhibitory gene expression | 7 | 12.5 | 6.25 | 18.75 | 12.5 | - | - | - | - | 12.5 | 25 | 12.5 |
| Activator/DNA/mRNA/Protein | |||||||||||||