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. 2017 Dec 21;12(12):e0189911. doi: 10.1371/journal.pone.0189911

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© 2017 Chen et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (A) H+E and Oil Red O staining of liver tissue from ovariectomized animals treated with various estrogens. Quantification of lipid droplet size (B) and number (C) by Fiji software. (D) Pearson correlations for lipid droplet size, body weight change, liver weight, and lipid droplet number were calculated. Statistical significance was established at α = 0.05. Pairwise t tests with a Bonferroni correction were used to identify treatments that were significantly different from Veh (***P <0.001, ****P<0.0001).