Skip to main content
. 2017 Dec 21;12(12):e0190009. doi: 10.1371/journal.pone.0190009

Fig 7. Validation of inflammatory mediators genes.

Fig 7

A: Mcp1, monocyte chemoattractant protein-1. B: Vcam1, vascular cell adhesion molecule-1. C: Tgfb1, transforming growth factor-β1. D: Thbs1, thrombospondin-1. Bars represent mRNA levels by quantitative polymerase chain reaction in the left renal cortex and outer medulla normalised to Gapdh mRNA. All values are expressed as mean ± SEM. Group means were compared using two-way ANOVA followed by Bonferroni’s multiple comparison post-test. * P < 0.05, ** P < 0.01, *** P < 0.005 and **** P < 0.0001. Number of animals: sham, UNx and IR groups (n = 8), IR+UNx (n = 6). IR, ischemia-reperfusion; UNx, unilateral nephrectomy.