Table 3. Changes in outcome measures.

	UNx vs sham	IR vs sham	IR+UNx vs sham	IR+UNx vs IR
DCE-MRI, GFR [mL/s]	↔	↔	↓	↔
DCE-MRI, RBF [mL/s]	↔	↔	↔	↓
Slice-selective T1-weighted-MRI, T1 [ms]	↑	↔	↔	↑
BOLD-MRI, R2* [s-1]	↔	↓	↓	↔
23Na-MRI, CM sodium gradient	↔	↓	↓	↔
Morphologic injury	↔	↑	↑	↓
Pro-inflammatory gene expression	↔	↑	↑	↓
Pro-fibrotic gene expression	↔	↑	↑	↓

Arrow indicates if the change was positive or negative compared with sham or control ischemic group, or if no change was present. CM, cortico-medullary. Please refer to Figs 2 and 5–7 for details.