. 2017 Dec 21;12(12):e0189822. doi: 10.1371/journal.pone.0189822

Table 2. The chemical reactions of muscle phosphagen and glycolytic energy systems^*.

Reaction	Enzyme	ΔH⁺
*Phosphagen System*
HCrP + ADP + H⁺ ↔ Cr + ATP	Creatine kinase	+1
ADP + ADP ↔ ATP + AMP	Adenylate kinase	0
AMP + H⁺ ↔ IMP + NH₄	AMP deaminase	+1
ATP + H₂O ↔ ADP + Pi +H⁺	ATPase	-1
*Glycogenolysis*
Glycogen(n) + HP ↔ Glycogen(n-1) + G1P	Phosphorylase	0
G1P ↔ G6P	Phosphogluco mutase	0
*Glycolysis*
Glucose + ATP ↔ G6P + ADP + H⁺	Hexokinase	-1
G6P ↔ F6P	Glucose-6-phosphate isomerase	0
F6P + ATP ↔ F1,6P + ADP + H⁺	Phosphofructokinase	-1
F1,6P ↔ DHP + G3P	Aldolase	0
DHP ↔ G3P	Triosephosphate Isomerase	0
G3P + HPi + NAD+ ↔ 1,3BPG + NADH + H⁺	Glyceraldehyde-3-phosphate dehydrogenase	-1
1,3BPG + ADP ↔ 3PG + ATP	Phosphoglycerate kinase	0
3PG ↔ 2PG	Phosphoglycerate mutase	0
2PG + ADP ↔ PEP	Enolase	0
PEP + ADP + H+ ↔ Pyr + ATP	Pyruvate kinase	+1
*Lactate Production*
Pyr + NADH + H⁺ ↔ La + NAD⁺	Lactate dehydrogenase	+1

* ΔH⁺ = reference proton load value prior to adjustment for partial ionization (-’ve = proton release, +‘ve = proton consumption); See Table 1 for metabolite abbreviation definitions.

Table 2. The chemical reactions of muscle phosphagen and glycolytic energy systems*.

Table 2. The chemical reactions of muscle phosphagen and glycolytic energy systems^*.