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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Nov 11;495(1):553–559. doi: 10.1016/j.bbrc.2017.11.071

Fig. 1. Reduced size, weight, and bone length in global Pit-2 homozygous knockout mice.

Fig. 1

(A) Genomic DNA determined by RT-PCR in WT and PiT-2 KO mice. (B) Gross appearance of female mice. (C) Body weight of male and female mice. (D) Representative rendered micro CT scan showing the various bone length measurements taken. Length of (E) vertebral column, (F) femur, and (G) tibia of male mice. Data are presented as mean ± S.E.M (n=5). A two-tailed P-value < 0.05 was considered statistically significant. *P<0.05 versus WT group. #P<0.05 versus female WT group. Micro CT, micro-computed tomography; PiT-2 KO, PiT-2 homozygous knockout; RT-PCR, reverse transcriptase-polymerase chain reaction; WT, wild-type.