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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Nov 11;495(1):553–559. doi: 10.1016/j.bbrc.2017.11.071

Fig. 2. Global PiT-2 homozygous knockout mice exhibit reduced mandibular size but relatively elongated condylar processes.

Fig. 2

(A) Representative image of a 3D rendered mandible showing the five linear measurements collected from mandibles. (B) Scaled lateral views of representative mandibles of wildtype and PiT-2 KO male mice. The overlay of representative WT (green) and PiT-2 KO (red) mandibles after scaling shows the relative condylar process extension in PiT-2 KO mice (red arrowhead). (C) Comparison of five mandibular distances (denoted in (A)) between WT and PiT-2 KO mice. Data are presented as mean ± S.E.M (n= 3). Differences between groups were analyzed by an un-paired t-test. A two-tailed P-value < 0.05 was considered statistically significant. *P<0.05 versus WT group. PiT-2 KO, PiT-2 homozygous knockout; WT, wildtype.