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. 2017 Sep 21;7(1):e1372081. doi: 10.1080/2162402X.2017.1372081

Table 1b.

Relapsed patients (A-D from Table 1a).

Patient Time of relapse Site(s) of relapse Treatment Treatment duration Response RFS from start of treatment* (months) RFS from end of treatment* (months)
A 1 mo after last vaccine Lung, spleen Ipilimumab + nivolumab 14 months CR 44 30
8.3 mo from resection
B 1 mo after last vaccine Liver, spleen Ipilimumab + nivolumab 4 months CR 43 39.3
7.4 mo from resection
C 1 mo after last vaccine Bone Multiple including ipilimumab & pembrolizumab 16 months total POD NA NA
5.2 mo from resection
D On study after 3rd vaccine Skin, CNS Lirilumab + nivolumab One dose CR 40.2 40.2
4 mo from resection

CR = complete response; EOS = end of study; F/u = follow-up; NA = not applicable; NED = no evidence of disease; POD = progression of disease; RFS = recurrence-free survival

*

cutoff date 07/01/2017, approximately 31 months from the end of the study