Scheme 2. Synthesis of quinazolinone diaryl urea derivatives QDAU1-10a.
aReagents and conditions: (a) HCONH2, MW, 150°C,1.5h; (b) BTC, Et3N, 0°C to room temperature; (c) Pd(PPh3)4, K2CO3, H2O/dioxane, 100°C.
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