Table 3. RTKs selectivity profile of the most active compounds (IC50, nM).
| Compound | VEGFR-1 | PDGFR-β | FGFR-1 | FGFR-4 | B-Raf | EGFR | c-Kit |
|---|---|---|---|---|---|---|---|
| QDAU4 | 68.3 | >500 | 165.9 | 83.4 | 136 | 113 | >500 |
| QDAU5 | 192 | 98.5 | 176.2 | >500 | >500 | 98.8 | 142 |
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