Table 3. BMI and CT-estimated obesity parameters in relation to clinicopathological factors and hormone receptor status for 227 endometrial cancer patients.
| BMI | WC | TAV | VAV | SAV | VAV% | LD | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | median | p | median | p | median | p | median | p | median | p | median | p | median | p | |
| (kg/m2) | (cm) | (ml) | (ml) | (ml) | (%) | (HU) | |||||||||
| Histological subtype & grade (n=225) | 0.02 | 0.02 | 0.01 | 0.03 | 0.01 | 0.54 | 0.01 | ||||||||
| Endometrioid grade 1-2 | 152 (68) | 28.0 | 98 | 10,302 | 3,647 | 6,032 | 37 | 99 | |||||||
| Endometrioid grade 3 | 32 (14) | 25.2 | 87 | 6,645 | 2,241 | 4,310 | 36 | 109 | |||||||
| Non-endometrioid | 41 (18) | 25.6 | 91 | 7,978 | 2,849 | 4,476 | 39 | 106 | |||||||
| FIGO stage | 0.63 | 0.74 | 0.90 | 0.79 | 0.66 | 0.21 | 0.57 | ||||||||
| I+II | 201 (89) | 26.1 | 96 | 8,984 | 3,390 | 5,613 | 37 | 102 | |||||||
| III+IV | 26 (11) | 26.7 | 96 | 8,596 | 3,160 | 4,890 | 40 | 102 | |||||||
| Ploidy (n=119) | 0.29 | 0.30 | 0.37 | 0.98 | 0.19 | 0.01 | 0.46 | ||||||||
| Diploid | 94 (79) | 26.4 | 96 | 9,438 | 3,439 | 5,716 | 37 | 99 | |||||||
| Aneuploid | 25 (21) | 26.1 | 92 | 8,024 | 3,295 | 4,476 | 42 | 102 | |||||||
| Age (median) | 0.04 | 0.15 | 0.35 | 0.21 | 0.02 | <0.001 | 0.17 | ||||||||
| < 67 years | 108 (47) | 26.8 | 96 | 8,920 | 3,159 | 6,084 | 34 | 101 | |||||||
| ≥ 67 years | 121 (53) | 26.4 | 95 | 9,174 | 3,748 | 5,041 | 40 | 102 | |||||||
| ERα expression, IHC (n=170) | 0.36 | 0.15 | 0.20 | 0.23 | 0.27 | 0.99 | 0.10 | ||||||||
| Positive | 114 (67) | 27.1 | 98 | 9,627 | 3,464 | 5,693 | 37 | 100 | |||||||
| Negative | 56 (33) | 26.0 | 94 | 8,152 | 2,951 | 4,820 | 39 | 105 | |||||||
| PR expression, IHC (n=170) | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 | 0.37 | 0.002 | ||||||||
| Positive | 131 (77) | 28.0 | 98 | 10,386 | 3,596 | 6,155 | 37 | 100 | |||||||
| Negative | 39 (23) | 24.6 | 88 | 6,180 | 2,273 | 3,642 | 39 | 106 | |||||||
| AR expression, IHC (n=169) | 0.01 | 0.002 | 0.004 | 0.004 | 0.01 | 0.47 | 0.01 | ||||||||
| Positive | 107 (63) | 28.0 | 98 | 10,420 | 3,831 | 6,120 | 37 | 98 | |||||||
| Negative | 62 (37) | 25.1 | 91 | 7,957 | 2,811 | 4,557 | 38 | 106 | |||||||
Abbreviations: AR: Androgen receptor; BMI: Body mass index; CT: Computed tomography; ERα: Estrogen receptor alpha; FIGO: International federation of gynecology and obstetrics; HU: Hounsfield units; IHC: Immunohistochemistry; LD: Liver density; PR: Progesterone receptor; p: p-values (Independent samples Kruskal-Wallis test for histological subtype and grade, remaining p-values: Mann-Whitney U test); SAV: Subcutaneous abdominal fat volume; TAV: Total abdominal fat volume; VAV: Visceral abdominal fat volume; VAV%: Visceral fat percentage; WC: Waist circumference.
BMI: data missing for one patient.
Liver density: data missing for two patients.