Table 4. Prognostic impact of VAV% adjusted for FIGO stage, age, histological subtype and grade, for 225 endometrial cancer patients (Cox proportional hazards regression model).
| n | Unadjusted HR | 95% CI | p-value | Adjusted HR | 95% CI | p-value | |
|---|---|---|---|---|---|---|---|
| FIGO stage | <0.001 | 0.003 | |||||
| Stage I | 178 | 1 | 1 | ||||
| Stage II | 21 | 1.20 | 0.27 – 5.26 | 0.813 | 0.53 | 0.11 – 2.59 | 0.431 |
| Stage III | 21 | 6.61 | 2.85 – 15.29 | <0.001 | 4.44 | 1.75 – 11.26 | 0.002 |
| Stage IV | 5 | 11.54 | 3.31 – 40.31 | <0.001 | 3.11 | 0.80 – 12.10 | 0.101 |
| Histological subtype & grade | <0.001 | 0.001 | |||||
| Endometrioid grade 1-2 | 152 | 1 | 1 | ||||
| Endometrioid grade 3 | 32 | 2.22 | 0.68 - 7.20 | 0.185 | 1.12 | 0.31 - 4.06 | 0.860 |
| Non-endometrioid | 41 | 7.59 | 3.32 - 17.36 | <0.001 | 4.91 | 1.94 - 12.42 | 0.001 |
| Age | 225 | 1.05 | 1.01 – 1.09 | 0.008 | 1.02 | 0.97 −1.07 | 0.400 |
| VAV% | 225 | 1.07 | 1.03 - 1.12 | 0.001 | 1.05 | 1.00 - 1.11 | 0.041 |
Abbreviations: CI: Confidence interval; FIGO: International federation of gynecology and obstetrics; HR: Hazard ratio; VAV%: Visceral fat percentage. p-value: Wald test.