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. 2017 Oct 26;8(62):105196–105210. doi: 10.18632/oncotarget.22111

Figure 1. Loss of Spinophilin in human tumors.

Figure 1

(A and B) Representative photo of different lung tumors with different Spinophilin levels. (C) The levels of Spinophilin mRNA in a cohort of 72 human lung tumors described in reference [7] were analyzed according to the procedure described in M&M. The mean value of mRNA levels of Spinophilin in all samples calculated and tumors distributed according to this mean value. High Spinophilin > mean value; Low Spinophilin > mean value. (D) Analysis of Spinophilin mRNA levels in samples from the cohort of [66]. (E) Analysis of Spinophilin mRNA levels in samples from the cohort of [66]. (E) Analysis of Spinophilin mRNA levels in samples from the cohort of [66]. In all three cases (D, E and F) the differences of the Spinophilin mRNA levels between ADC and SCC were statistically significant (p<0.05) ADC: Lung Adenocarcinoma; LCLC: Large Cell Lung Carcinoma; SCC: Squamous Cell Lung Carcinoma.