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. 2017 Oct 27;8(62):105262–105275. doi: 10.18632/oncotarget.22166

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Copyright: © 2017 Guan et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A and B) MTT assays indicated that the growth rates decreased in RDH10-silenced U87 (A) and U251 (B) cells. (C and D) RDH10 knockdown induced apoptosis in U87 (C) and U251 (D) cells. (E and F) RDH10 knock- down induces an S and G2/M cell cycle arrest in U87 (E) and U251 (F) cells. (G and H) Transwell Matrigel invasion assays showed that the number of invasive cells in the RDH10 siRNA group was decreased significantly compared with that in the control group for U87 (G) and U251 (H) cells. All experiments were repeated at least three times. Data are shown as mean ± SD, ^**P < 0.01.