Table 3. The effects of VEGFA rs833061 polymorphism on ORR, DCR and PFS among CRC patients receiving bevacizumab treatment.
Genotypes | ORR | DCR | PFS | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | P | ORa | Pa | OR | P | ORa | Pa | HR | P | HRb | Pb | |
TT | 0.220 (0.044-1.103) | 0.048 | 0.224 (0.044-1.134) | 0.071 | 0.129 (0.031-0.532) | 0.002 | 0.124 (0.030-0.519) | 0.004 | 0.299 (90.141-0.634) | 0.002 | 0.299 (0.141-0.634) | 0.002 |
TC | 0.159 (0.029-0.861) | 0.021 | 0.159 (0.029-0.871) | 0.034 | 0.241 (0.054-1.070) | 0.052 | 0.230 (0.051-1.038) | 0.056 | 0.449 (0.203-0.991) | 0.048 | 0.449 (0.203-0.991) | 0.048 |
CC | Reference | Reference | Reference |
Notes: a: calculated by logistic regression analysis; b: analyzed by cox-regression analysis.