Figure 1. Indirubin attenuates the morbidity and mortality caused by influenza infection in stressed mice.

Chemical structure of indirubin (A). Effects of indirubin on body weight changes (B), morbidity (C) and survival rate (D) of mice after influenza infection. “-” indicates no treatment. Indirubin-H and Indirubin-L respectively represent the higher dose of indirubin (5 mg·kg⁻¹·d⁻¹) and the lower dose of indirubin (2.5 mg·kg⁻¹·d⁻¹). The difference was considered statistically significant at ^†P < 0.05 vs. Virus group; ^*P < 0.05 and ^**P < 0.01 vs. “Stress+Virus” group. Data were obtained from 10 - 14 animals in each group.