Figure 3. Reduction of PD-L1 expression under RXDX-106 exposure in sensitive cell line.
(A) Basal expression of PD-L1 in gastric cancer cell lines. (B) RXDX-106 affects STAT3 and PD-L1. For Western blotting, cells were exposed to RXDX-106 at 1 μM concentration for 3 days. β-actin used as loading control. (C) Representative photomicrographs (X40) of SNU-638 and SNU-668 cell pellets stained by the PD-L1 ICC assay.