Table 3. Result of the univariate analysis of overall survival in NPC patients.
Characteristic | Hazard ratio | 95% CI | P-value |
---|---|---|---|
Sex (male vs. female) | 1.435 | 0.925-2.227 | 0.107 |
Age (≥60 vs. < 60 years) | 1.719 | 1.035-2.852 | 0.036 |
Smoking (yes vs. no) | 1.448 | 0.985-2.129 | 0.060 |
BMI (kg/m2) (>23.7 vs. ≤23.7) | 1.335 | 0.917-1.943 | 0.132 |
Diabetes (yes vs. no) | 1.767 | 0.856-3.647 | 0.124 |
Family history of NPC (yes vs. no) | 0.986 | 0.563-1.728 | 0.962 |
KPS (≤80 vs. > 80) | 1.168 | 0.805-1.696 | 0.414 |
Undifferentiated cancer (yes vs. no) | 0.948 | 0.652-1.380 | 0.782 |
T stage(T3-4 vs. T1-2) | 4.786 | 2.963-7.728 | <0.001 |
N stage (N2–3 vs. N0–1) | 4.099 | 2.536-6.651 | <0.001 |
Clinical stage (III–IVB) vs. (I–II) | 43.441 | 10.284 – 183.507 | <0.001 |
CCRT (no vs. yes) | 0.936 | 0.620-1.413 | 0.753 |
IMRT (no vs. yes) | 1.292 | 0.839-1.988 | 0.245 |
PLT (>266 vs. ≤266) (×109/L) | 1.979 | 1.361-2.877 | <0.001 |
MPV (>10.6vs.≤10.6) fL | 0.385 | 0.257-0.577 | <0.001 |
PDW (>16.3 vs. ≤16.3) fL | 2.986 | 2.030 – 4.394 | <0.001 |
PLR (>130.22 vs. ≤130.22) | 2.890 | 1.835 – 4.553 | <0.001 |
EBV DNA (high vs. low) (copies/mL) | 2.192 | 1.418 – 3.388 | <0.001 |
Abbreviations: see Table 1.