Table 3. Levels of estrogen and its metabolites in the lung of never- vs. current-smoking men*.

	Normal (pg/g tissue)			Tumor (pg/g tissue)
	N n = 7	C n = 10	P N vs. C	N n = 5	C n = 10	P N vs. C
E1	5.47	6.46	0.23	5.20	6.79	0.08
E2	8.73	9.42	0.19	8.96	10.15	0.17
E3	2.14	2.67	0.81	2.26	2.90	0.59
2OHE1	1.69	1.98	0.42	1.92	2.09	0.68
2OHE2	0.72	0.68	0.81	0.76	0.74	0.86
4OHE1	0.20	0.21	0.54	0.23	0.24	0.77
4OHE2	0.10	0.10	0.81	0.13	0.12	0.95
2OME1	0.51	0.52	0.89	0.49	0.63	0.77
2OME2	0.25	0.30	0.60	0.27	0.34	0.25
2OHEs/Total	0.12	0.12	0.19	0.12	0.11	0.25
4OHEs/Total	0.01	0.01	0.11	0.02	0.02	0.13
2OMEs/Total	0.04	0.04	0.74	0.04	0.04	0.77
4OHEs/2OHEs	0.12	0.12	0.89	0.14	0.13	0.95

^*Values represent the medians. Statistical comparisons were based on the Wilcoxon rank sum test. N: never smokers; C: current smokers.