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. 2017 Oct 30;8(63):106935–106947. doi: 10.18632/oncotarget.22149

Figure 4. Reduction of ezrin expression inhibits CRC cell migration and invasion in vitro.

Figure 4

(A, C) Wound healing assays of DLD1 (A) and LoVo (C) CRC cells transfected with control or ezrin-specific siRNA. Representative images were acquired at 0 h and 48 h after wounding. (B, D) Quantitation of migration in the assays represented in A and C. The y-axis represents migration rates relative to control cells. (E, G) Transwell invasion assays of DLD1 (E) and LoVo (G) cells transfected with control or ezrin-specific siRNA. Phase contrast micrographs at ×40 magnification. (F, H) Quantitation of invasion in the assays represented in E and G. The y-axis represents the ratio of the number of invading cells per control chamber cells. All assays were replicated and the results are presented as the mean ± SEM.