Figure 6. Representative nonlinear optical images of three types of fibrotic response after neoadjuvant therapy in rectal carcinoma and corresponding H&E-stained images.

(A) SHG image of mature fibrotic stroma and (B) corresponding H&E-stained image; (C) SHG image of intermediate fibrotic stroma and (D) corresponding H&E-stained image; (E) SHG image of immature fibrotic stroma and (F) corresponding H&E-stained image. Scale bar: 50 μm.