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Patritumab enhances the activity of vincristine and cyclophosphamide. Mice bearing ES-4 Ewing sarcoma xenografts were treated as described in Materials and Methods. Growth of individual tumors is presented. Tumor volumes (cm3) are plotted against time (weeks) (P, patritimab). Right panels show Kaplan-Maier Event Free survival (%); control (black), cytotoxic drug (blue), cytotoxic drug + patritumab (P; red).
