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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Bipolar Disord. 2017 Oct 11;19(8):661–675. doi: 10.1111/bdi.12560

Table 2.

Significant Three-Way Interaction Clusters

Peak Coordinates
Region Laterality x y z Brodmann Area Cluster Size
Right VS Seed
Post. Temporal Fusiform Gyrus L −44 −24 −24 20 150
Post. Temporal Fusiform Gyrus R 28 −34 −26 N/A 130
Post. Inferior Temporal Gyrus L −46 −26 −26 20 103
Post. Inferior Temporal Gyrus R 42 −30 −26 37 37
Amygdala L −20 −12 −12 N/A 214
Lingual Gyrus R 32 −42 −6 36 73
Med. Frontopolar Cortex 8 46 −16 11 379
Ventral Striatum R 12 12 −6 48 30
Left VS Seed
Ant. Temporal Fusiform Gyrus1 L −26 −10 −40 36 81
Ant. Temporal Fusiform Gyrus R 36 −4 −34 20 100
Post. Inferior Temporal gyrus L −46 −26 −26 20 263
Post. Inferior Temporal gyrus R 44 −16 −36 20 24
Ant. Insula R 42 2 −8 13 215
Orbitofrontal Cortex L −12 16 −16 11 19
Orbitofrontal Cortex R 24 20 −16 N/A 76
Ant. Parahippocampal Gyrus L −26 −12 −32 36 192
Ant. Parahippocampal Gyrus R 30 0 −34 36 38
Amygdala L −18 −12 −12 N/A 131
Lingual Gyrus R 30 −40 −6 36 97
Ventral Striatum L −12 10 −6 N/A 50
Ventral Striatum1 R 12 12 −6 48 58

Note: Peak coordinates for main clusters (≥100 voxels) are reported in Montreal Neurological Institute (MNI) space (x, y, z). Results are cluster corrected at p<0.05. Brodmann Areas indicated correspond to the peak coordinates for each cluster.

1

These regions were no longer significant after clinical covariates (subthreshold depression symptoms, presence vs. absence of antipsychotic medication, and presence vs. absence of comorbid anxiety) were entered into the regression model.