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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Hepatology. 2017 Nov 14;67(1):10–12. doi: 10.1002/hep.29481

Figure 1. Green tea for the chemoprevention of hepatocellular carcinoma.

Figure 1

Gamma-hydroxy-1,N2-propanodeoxyguanosine (γ-OHPdG), a mutagenic lipid peroxidation-induced DNA adduct correlates with hepatocellular carcinoma (HCC) incidence in experimental murine models of HCC. Theaphenon E administration reduced the HCC tumor burden and γ-OHPdG levels, suggesting that the chemopreventive effect of green tea might be mediated by Theaphenon E by decreasing γ-OHPdG in liver DNA and consequent DNA mutations