Table 1. Correlations between adiposity traits and measures of metabolic health in HS rats.
Body Weight | BMI Tail End | BMI Tail Base | EpiFat | RetroFat | |
---|---|---|---|---|---|
Fasting Glucose | 0.1453 (0.0012) | 0.0952 (0.76) | 0.0886 (1) | 0.1931 (3.24e-05) | 0.1132 (0.1009) |
Fasting Insulin | 0.1936 (3.48-07) | 0.1153 (0.091) | -0.0248 (1) | 0.4314 (1.35e-31) | 0.3516 (4.75e-27) |
Fasting Total Cholesterol | 0.2644 (7.10e-11) | 0.2428 (5.75e-09) | 0.1172 (0. 39) | 0.2535 (6.85e-10) | 0.3529 (1.02e-20) |
Fasting Triglycerides | 0.1291 (0.12) | 0.2426 (6.07e-09) | 0.0950 (1) | 0.3096 (1.75e-15) | 0.3499 (2.55e-20) |
Glucose AUC | 0.1378 (0.0040) | 0.1259 (0.0214) | 0.0652 (1) | 0.1663 (0.0016) | 0.1718 (1.71e-05) |
Insulin AUC | 0.2937 (5.67e-18) | 0.2238 (7.99e-10) | 0.0312 (1) | 0.4670 (2.71e-37) | 0.4397 (8.79e-44) |
QUICKI | -0.2042 (3.91e-08) | -0.1198 (0.0523) | 0.0211 (1) | -0.4338 (5.24e-32) | -0.3544 (1.57e-27) |
IGI | 0.1629 (0.0001) | 0.1220 (0.0430) | 0.0001 (1) | 0.2475 (5.46e-09) | 0.2038 (5.46e-08) |
Spearman's rank correlation with Bonferonni-adjusted p-values in parentheses (bold if <0.05). To mitigate potentially confounding effects of experimental covariates, correlations are performed on phenotypic residuals (ie, on the residuals after regressing out covariate effects from the rank-inverse normal transformed phenotype).