Tissues from research-consented organ donors were obtained for analysis
of immune cells from 291 donors between February, 2011 and October 2016. (A)
Graph shows number of donors of each age spanning 3 months to 93 years of age
(n=291), stratified into the following age categories: Pediatric, 0–15
years of age; Young adult, 16–35 years of age; Middle years,
36–65 years of age; Senior, > 65-years of age. (B) Graph shows
stratification of gender (left) and cause of death (right) by age range. (C) Bar
graphs showing eight clinical characteristics stratified by donor age category.
Clinical characteristics include: non-cerebrovascular accident (CVA) as cause of
death (COD); need for cardiopulmonary resuscitation (CPR); brain death duration
greater than 48 hours (BDD>48hrs); length of stay (LOS) greater than one
week; administration of steroids (1g Solumedrol every 24 hours) after the
diagnosis of brain death; presence of acute lung injury (ALI) as diagnosed by
Berlin criteria (see supplemental methods); whether or not the donor received a packed
red blood cell or platelet transfusion during their hospitalization
(“Transfusion”); and, whether or not the donor had a positive
blood or urine culture at any point during their hospitalization (Culture
positive).