Table 4.
Mean number of children by sex and data source
| Data source | N | Mean (S.E.) | Percent distribution (S.E.) for number of live-born childrenb | ||||
|---|---|---|---|---|---|---|---|
| None | 1 | 2 | 3 | 4+ | |||
| Males (all) | |||||||
| National dataa, 2006–2010 | − | 0.9 (0.0) | 55.2 (1.1) | 15.8 (0.6) | 17.0 (0.7) | 7.9 (0.5) | 4.1 (0.3) |
| Fabry data, 2015 | 133 | 1.1 (0.1) | 43.6 (4.3) | 17.3 (3.3) | 30.8 (4.0) | 6.0 (2.1) | 2.3 (1.3) |
| Females (all) | |||||||
| National dataa, 2006–2010 | − | 1.3 (0.0) | 44.4 (1.1) | 16.2 (0.5) | 21.0 (0.8) | 11.5 (0.5) | 6.9 (0.5) |
| Fabry data, 2015 | 230 | 1.8 (0.1) | 22.6 (2.8) | 20.4 (2.7) | 30.9 (3.1) | 13.9 (2.3) | 12.2 (2.2) |
| White, non-Hispanic (single race) | |||||||
| Women | |||||||
| National dataa, 2006–2010 | − | 1.1 (0.0) | 47.7 (1.4) | 15.7 (0.7) | 21.8 (1.0) | 10.6 (0.6) | 4.2 (0.4) |
| Fabry data, 2015 | 201 | 1.8 (0.1) | 23.4 (3.0) | 19.4 (2.8) | 31.8 (3.3) | 13.4 (2.4) | 11.9 (2.3) |
| Men | |||||||
| National dataa, 2006–2010 | − | 0.8 (0.0) | 58.9 (1.5) | 14.9 (0.9) | 17.0 (1.0) | 6.6 (0.6) | 2.6 (0.3) |
| Fabry data, 2015 | 120 | 1.1 (0.1) | 44.2 (4.6) | 18.3 (3.6) | 28.3 (4.1) | 6.7 (2.3) | 2.5 (1.0) |
Abbreviations: SE standard error
aNational data is based on a survey of 10,403 men and 12,279 women which were weighted to reflect approximately 62 million men and 62 million women aged 15–44
bChi-square tests were used to compare the percent distribution of number of live-born children among patients with Fabry’s disease to corresponding national data. All statistical comparisons were significant as a result of the large sample size in the national data