Table 5.
Comparison of posterior pole characteristics according to the different locations of the DPE in myopic non-glaucomatous patients and the myopic glaucomatous eyes*.
| Near Fovea | P value † | Superior Hemisphere | P value† | Inferior Hemisphere | P value † | Near Disc | P value ∥ | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Myopes without NTG (n = 125) | Myopes with NTG (n = 129) | Myopes without NTG (n = 125) | Myopes with NTG (n = 129) | Myopes without NTG (n = 125) | Myopes with NTG (n = 129) | Myopes without NTG (n = 125) | Myopes with NTG (n = 129) | |||||
| Number of eyes | 39 | 67 | 7 | 7 | 54 | 31 | 25 | 24 | ||||
| Inferotemporal RNFL defect, number (%) | 51 (76.1%) | 4 (57.1%) | 22 (71.0%) | 16 (66.7%) | ||||||||
| Age, years | 42.6 ± 12.0 | 43.5 ± 10.2 | 0.183 | 49.5 ± 7.8 | 45.0 ± 10.1 | 0.535 | 43.1 ± 13.5 | 46.1 ± 13.7 | 0.113 | 47.4 ± 8.1 | 50.0 ± 9.8 | 0.024 ‡ |
| SE, diopter | −4.2 ± 3.2 | −5.1 ± 3.5 | 0.184 | −2.3 ± 1.8 | −1.0 ± 1.9 | 0.165 | −4.6 ± 4.9 | −5.5 ± 3.3 | 0.195 | −4.6 ± 4.9 | −4.8 ± 4.4 | 0.828 |
| Axial length, mm | 26.2 ± 1.3 | 26.6 ± 1.1 | 0.128 | 25.3 ± 1.2 | 25.4 ± 1.3 | 1.000 | 26.1 ± 1.2 | 26.9 ± 1.4 | 0.005 ‡ | 25.8 ± 1.3 | 26.8 ± 1.5 | 0.009 ‡ |
| Visual field MD, dB | −1.4 ± 1.6 | −6.3 ± 4.7 | <0.001 ‡ | −1.7 ± 2.2 | −2.9 ± 4.1 | 0.318 | −1.5 ± 1.9 | −6.6 ± 6.3 | <0.001 ‡ | −1.4 ± 1.9 | −6.1 ± 6.4 | <0.001 ‡ |
| Average RNFL thickness, μm | 93.2 ± 12.9 | 72.9 ± 12.4 | <0.001 ‡ | 99.1 ± 9.8 | 85.1 ± 13.2 | 0.073 | 94.4 ± 13.2 | 74.3 ± 15.6 | <0.001 ‡ | 94.8 ± 18.3 | 71.4 ± 18.9 | <0.001 ‡ |
| Disc-DPE distance, mm | 4.54 ± 0.58 | 4.51 ± 0.75 | 0.828 | 3.61 ± 0.95 | 3.78 ± 0.77 | 0.620 | 3.84 ± 1.22 | 4.50 ± 0.97 | 0.012 ‡ | 1.91 ± 0.51 | 2.06 ± 0.99 | 0.575 |
| Disc-DPE depth, mm | 0.20 ± 0.15 | 0.21 ± 0.14 | 0.882 | 0.064 ± 0.07 | 0.093 ± 0.14 | 0.318 | 0.13 ± 0.16 | 0.21 ± 0.21 | 0.053 | 0.019 ± 0.18 | 0.022 ± 0.03 | 0.001 ‡ |
| Disc–DPE angle (°) | 12.97 ± 9.42 | 14.19 ± 8.86 | 0.504 | −23.50 ± 8.17 | −21.07 ± 10.52 | 0.620 | 37.31 ± 20.12 | 37.78 ± 15.86 | 0.910 | 35.42 ± 31.93 | 59.68 ± 52.28 | 0.050 |
| Disc-foveal angle (°) | 6.45 ± 3.09 | 7.04 ± 4.06 | 0.434 | 7.75 ± 3.40 | 5.65 ± 5.04 | 0.383 | 7.84 ± 3.25 | 9.17 ± 3.45 | 0.079 | 7.64 ± 4.26 | 8.31 ± 3.43 | 0.535 |
| Disc torsion angle (°) | 7.18 ± 13.58 | 3.61 ± 21.96 | 0.362 | −21.43 ± 9.88 | −15.00 ± 33.54 | 0.318 | 24.79 ± 26.1 | 27.09 ± 29.18 | 0.710 | 20.24 ± 38.74 | 19.67 ± 28.56 | 0.802 |
| Disc ovality index | 1.29 ± 0.25 | 1.40 ± 0.34 | 0.066 | 1.18 ± 0.11 | 1.35 ± 0.18 | 0.047 ‡ | 1.23 ± 0.14 | 1.39 ± 0.28 | 0.001 ‡ | 1.22 ± 0.15 | 1.23 ± 0.20 | 0.812 |
| Horizontal tilt angle (°) | 12.17 ± 6.97 | 18.34 ± 6.98 | <0.001 ‡ | 11.43 ± 9.74 | 10.85 ± 7.88 | 0.902 | 12.11 ± 8.86 | 16.83 ± 10.01 | 0.027 ‡ | 11.84 ± 13.99 | 16.67 ± 13.48 | 0.117 |
| Vertical tilt angle (°) | 4.18 ± 8.73 | 7.34 ± 11.53 | 0.141 | 0.86 ± 2.27 | 3.28 ± 5.96 | 0.620 | 8.44 ± 11.38 | 13.16 ± 11.36 | 0.015 ‡ | 8.44 ± 11.38 | 8.99 ± 11.79 | 0.739 |
SE: spherical equivalent; MD: mean deviation of perimetry; RNFL: retinal nerve fiber layer; DPE: deepest point of the eyeball. *Data are presented as mean ± standard deviation unless otherwise indicated. †Independent t-test for continuous variables. ‡Statistically significant values (P < 0.05) are shown in bold. §χ² test for categorical variables. ∥Mann-Whitney test for nonparametric statistical test.