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. 2017 Dec 21;7:17975. doi: 10.1038/s41598-017-18331-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Surface topography of the skin given by OCT. (b) Absorption from skin surface given by PAT. Four colored circles in (a) and (b) indicate the same features seen in OCT and PAT. (c) Transition zone en face view showing the same vessels resolved by both OCTA (green) and PAT (red). (d) Skin vasculature in gray scale between the depth range [0 0.5 mm] in z direction imaged by OCTA. (e) 3D view in -z direction for the blood vessel network. PAT and OCTA resolved vessels are colored gold and red, respectively. (f) Depth color coded image of skin vasculature between [0.5 mm, 1 mm] in z direction using fused OCTA/PAT volume. (g) Depth color coded image of skin vasculature between [1 mm, 3 mm] in z direction using fused OCTA/PAT volume. Scale bar = 1 mm.