Table 3.

Operational definition of composite outcome of interest.

Outcome component	Diagnosis descriptor	ICD-9-CM diagnosis code(s)*	Diagnosis position and type/Claim type	PPV/Sensitivity
Venous thromboembolism	Iatrogenic pulmonary embolism and infarction	415.11	Principal position inpatient discharge diagnosis/MAX inpatient, short-stay MedPAR, or long-stay MedPAR claim	~95%/~77%52
	Other pulmonary embolism and infarction	415.19
	Phlebitis and thrombophlebitis of femoral vein	451.11
	Other phlebitis and thrombophlebitis	451.19
	Phlebitis and thrombophlebitis of lower extremities, unspecified	451.2
	Phlebitis and thrombophlebitis of unspecified site	451.9
	Thrombophlebitis migrans	453.1
	Embolism and thrombosis of inferior vena cava	453.2
	Acute venous embolism and thrombosis of deep vessels of lower extremity	453.4X
	Acute venous embolism and thrombosis of other specified veins	453.8X
	Embolism and thrombosis of unspecified site	453.9
Ischemic stroke	Occlusion and stenosis of precerebral arteries**	433.X1		~88%/~74%56
	Occlusion of cerebral arteries	434.X†
	Acute, but ill-defined, cerebrovascular disease	436.X

ICD-9-CM = International Classification of Diseases 9^th Revision Clinical Modification; MAX = Medicaid Analytic Extract; MedPAR = Medicare Provider Analysis and Review; PPV = positive predictive value.

*X indicates wildcard, i.e., values ranging from 0–9.

**Excluding mentions of cerebral infarction.

^†Excluding 434.X0.