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. 2017 Dec 21;7:18010. doi: 10.1038/s41598-017-17947-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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SE-EPI and xSPEN diffusion maps overlaid on T2 anatomical images. Yellow arrows highlight challenging head regions including the eyes (a), the nose and nasal cavity (b,c and e), the cerebellum (d and g), brain stem (f), and the tongue area (h). Notice that maps are given for two scales, with the larger ADC range (0.3–4.7 × 10⁻³ mm²/s) applying to the framed white squares that include the eyes. In all cases the xSPEN axis run along the anterior-posterior direction; see Methods for additional scanning parameters.