Table 4.
Newborn screening analytes used in model development.
| Acyl-carnitines (n = 31) | C0 (carnitine) | C16 (hexadecanoylcarnitine) |
| C2 (acetylcarnitine) | C18 (octadecanoylcarnitine) | |
| C3 (propionylcarnitine) | C18:1 (octadecenoylcarnitine) | |
| C4 (butyrylcarnitine) | C18:2 (octadecadienylcarnitine) | |
| C5 (valerylcarnitine) | C4OH (hydroxybutyrylcarnitine) | |
| C5:1 (Tiglylcarnitine) | C5DC (glutarylcarnitine) | |
| C6 (hexanoylcarnitine) | C5OH (hydroxyvalerylcarnitine) | |
| C8 (octanoylcarnitine) | C6DC (methylglutarylcarnitine) | |
| C8:1 (octenoylcarnitine) | C14:OH (3-hydroxytetradecanoylcarnitine) | |
| C10 (decanoylcarnitine) | C16:OH (hydroxyhexadecanoylcarnitine) | |
| C10:1 (decenoylcarnitine) | C16:1OH (hydroxyhexadecenoylcarnitine) | |
| C12 (dodecanoylcarnitine) | C18OH (3-hydroxystearoylcarnitine) | |
| C12:1 (dodecenoylcarnitine) | C18:1OH (hydroxyoctadecenoylcarnitine) | |
| C14 (tetradecanoylcarnitine) | C3DC (malonylcarnitine) | |
| C14:1 (tetradecenoyl carnitine) | C4DC (methylmalonylcarnitine) | |
| C14:2 (tetradecadienylcarnitine) | ||
| Amino acids and related markers (n = 12) | Arginine | Tyrosine |
| Phenylalanine | Glycine | |
| Alanine | Argininosuccinate | |
| Leucine | Methionine | |
| Ornithine | Valine | |
| Citrulline | Succinylacetone | |
| Relative fetal-to-adult hemoglobin (Hb) level (n = 1) | Fetal hemoglobin (HbF + HbF1)/(Fetal hemoglobin (HbF + HbF1) + Adult hemoglobin (HbA)) | |
| Endocrine markers (n = 2) | 17-hydroxyprogesterone (17-OHP) | |
| Thyroid stimulating hormone (TSH) | ||
| Enzyme markers (n = 3) | Biotinidase (BIOT) | |
| Galactose-1-Phosphate Uridyltransferase (GALT) | ||
| Immunotripsinogen (IRT) | ||