Table 4. Models Assessing ET Patients and COs’ Depressive Symptoms.

	Wald Statistic (1 df)	Odds Ratio	95% Confidence Interval	p
Model 1: ET patient psychological suffering predicting depression
Self-reported psychological suffering	5.52*	1.42	(1.06, 1.91)	0.02
Tremor duration	0.01	1.00	(0.95, 1.06)	0.93
Tremor disability score	3.39	1.41	(0.98, 2.04)	0.07
Total tremor score	2.41	0.81	(0.61, 1.06)	0.12
Constant	3.84	0.00		0.05
Model 2: ET patient overall suffering predicting depression
Self-reported overall suffering	1.56	1.28	(0.86,1.90)	0.21
Tremor duration	0.36	1.01	(0.97, 1.06)	0.55
Tremor disability score	2.92	1.30	(0.96, 1.74)	0.09
Total tremor score	0.69	0.91	(0.74, 1.13)	0.41
Constant	3.83**	0.01		0.01
Model 3: CO perceived psychological suffering predicting depression
Perceived psychological suffering	8.96**	1.26	(1.08, 1.47)	0.00
Tremor duration	0.43	0.96	(0.96, 1.08)	0.51
Tremor disability score	0.47	0.69	(0.69, 1.19)	0.49
Total tremor score	4.92*	0.49	(0.49, 0.96)	0.03
Constant	2.41	25.71		0.12
Model 4: CO perceived overall suffering predicting depression
Perceived overall suffering	7.89**	2.62	(1.34, 5.13)	0.005
Tremor duration	1.16	1.03	(0.98, 1.09)	0.28
Tremor disability score	0.92	0.88	(0.68, 1.14)	0.34
Total tremor score	6.21*	0.65	(0.46, 0.91)	0.01
Constant	4.00*	0.05

Abbreviations: CO, Close Others; df, Degrees of Freedom; ET, Essential Tremor.

^**p<0.01;

^*p<0.05.