Table 3.

IC₅₀ values of the indicated compounds were determined using the hydrolysis of fluorogenic substrates for the trypsin‐like activity (VGR) of 20S immunoproteasomes or constitutive proteasomes derived from humans or mice

		LU‐005i	LU‐001i
Human	IP	4.7 ± 0.9 10−7 M	n.i.
	CP	3.1 ± 0.5 10−6 M	n.i.
Mouse	IP	1.8 ± 0.5 10−7 M	n.i.
	CP	n.i.	n.i.

IC₅₀ values ± SD are indicated. n.i., no inhibition observed below 1 μM.