FIG 1.
(A) Phylogenetic tree based on amino acid sequences showing the relationship of OXA-436, acquired OXA-48-like variants, and selected OXA-48-like variants from Shewanella spp. The tree is rooted at the midpoint. OXA-48-like variants devoid of carbapenemase activity are indicated with asterisks. (B) Alignment of the amino acid sequence of OXA-436 with the amino acid sequences of selected OXA-48-like variants. Conserved motifs are shaded in black. The secondary structural elements of OXA-48 are indicated above the sequences.
