FIG 1.

Chitotriosidase (CHIT) and AMCase levels after instillation of low-molecular-weight chitosan (LMWC) and oligosaccharide-lactate chitosan (OLC). (A) Activity measured at day 0 of CHIT in rat lungs instilled at day −2 with PBS, LMWC, and OLC, as indicated. As a reference value, chitotriosidase activity on day 3 in A. fumigatus-infected rats as measured by Verwer et al. (10) was used. (B) Activity measured at day 0 of AMCase in rat lungs instilled at day −2 with PBS, LMWC, and OLC, as indicated. As a reference value, chitotriosidase activity on day 3 in A. fumigatus-infected rats as measured by Verwer et al. (10) was used. au, arbitrary units.