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. 2017 Dec 21;62(1):e01179-17. doi: 10.1128/AAC.01179-17

FIG 1.

FIG 1

TBZ exposure causes morphophysiological changes in Cryptococcus gattii R265 and C. neoformans H99. (A to C) TBZ-adapted cells of C. gattii R265 exhibited increased cell diameter (A) and decreased surface/volume ratio (B) but unaltered capsule thickness (C) compared to nonadapted (NA) cells. (D) C. neoformans H99 presented the pseudohyphal form after TBZ adaptation. An India ink suspension was used. Bar, 10 μm. (E and F) The electronegativity of the cellular surface was not altered in C. gattii R265 (E); however, it was increased in TBZ-adapted cells of C. neoformans H99 (F). NA, nonadapted; A, TBZ adapted; **, P < 0.01; ***, P < 0.001.