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. 2017 Dec 21;62(1):e01513-17. doi: 10.1128/AAC.01513-17

FIG 2.

FIG 2

Fidaxomicin and OP-1118 inhibit toxin A- and B-induced IL-1β mRNA expression in human colonic explants. (A) Dose response of toxin A- and B-induced IL-1β mRNA expression. (B) Dose response of fidaxomicin and OP-1118 in toxin A-and B-induced IL-1β mRNA expression. (C) Dose response of toxin A-and B-induced IL-1β protein expression. (D) Dose response of fidaxomicin and OP-1118 in toxin A- and B-induced IL-1β protein expression. Each group consisted of 6 fresh human colonic explants. *, P < 0.05; **, P < 0.01; ***, P < 0.001.