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Fidaxomicin and OP-1118 inhibit toxin A- and B-induced NF-κB phosphorylation in human colonic explants and mouse ileal loops. The phosphorylated NF-κB signal in human colonic tissues (A) and mouse ileal loops (B) is shown in brown. (A) Each group consisted of 6 fresh human colonic explants. (B) Each group consisted of 6 mice. Magnification, ×200. Black bars, 100 μm.
