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Activity of 100 mg/kg meropenem alone and in combination with various doses of vaborbactam against K. pneumoniae KP1074 (meropenem MIC of ≥64 mg/liter; with 8 mg/liter vaborbactam, 0.5 mg/liter) in a neutropenic mouse thigh infection model. Treatment was administered as a single intraperitoneal dose at 2 h postinfection.
