Table 1.
Mean (standard deviation) cortical volumes (whole brain and each hemisphere) as a percentage of total intracranial volume in the total FTD cohort and TDP-43 subset
Frontal | Temporal | Parietal | Occipital | Cingulate | Insula | |
Total FTD cohort: whole brain | ||||||
AA | 9.3 (0.9) | 6.1 (0.8) | 5.5 (0.4) | 4.4 (0.4) | 1.44 (0.14) | 0.69 (0.12) |
AG/GG | 9.6 (1.0) | 6.3 (0.8) | 5.4 (0.6) | 4.4 (0.4) | 1.49 (0.14) | 0.73 (0.11) |
Total FTD cohort: left hemisphere | ||||||
AA | 4.6 (0.5) | 2.9 (0.5) | 2.7 (0.3) | 2.2 (0.2) | 0.68 (0.09) | 0.34 (0.06) |
AG/GG | 4.8 (0.5) | 3.0 (0.5) | 2.7 (0.3) | 2.2 (0.2) | 0.72 (0.08) | 0.36 (0.06) |
Total FTD cohort: right hemisphere | ||||||
AA | 4.7 (0.5) | 3.2 (0.4) | 2.8 (0.2) | 2.2 (0.2) | 0.76 (0.08) | 0.36 (0.07) |
AG/GG | 4.8 (0.6) | 3.2 (0.4) | 2.7 (0.3) | 2.2 (0.2) | 0.77 (0.09) | 0.37 (0.06) |
TDP-43 subset: whole brain | ||||||
AA | 9.4 (1.0) | 5.8 (0.9) | 5.4 (0.5) | 4.4 (0.4) | 1.42 (0.16) | 0.69 (0.08) |
AG/GG | 9.8 (1.0) | 6.0 (0.9) | 5.5 (0.4) | 4.4 (0.3) | 1.49 (0.14) | 0.72 (0.10) |
TDP-43 subset: left hemisphere | ||||||
AA | 4.6 (0.5) | 2.7 (0.6) | 2.6 (0.3) | 2.2 (0.2) | 0.66 (0.10) | 0.33 (0.05) |
AG/GG | 4.9 (0.5) | 2.8 (0.6) | 2.8 (0.3) | 2.2 (0.2) | 0.69 (0.08) | 0.35 (0.06) |
TDP-43 subset: right hemisphere | ||||||
AA | 4.8 (0.5) | 3.1 (0.4) | 2.8 (0.3) | 2.2 (0.2) | 0.76 (0.08) | 0.36 (0.05) |
AG/GG | 4.9 (0.5) | 3.2 (0.4) | 2.8 (0.3) | 2.2 (0.1) | 0.79 (0.09) | 0.37 (0.05) |
FTD, frontotemporal dementia.