Table 1.

Correlation between TBI severity (GCS score) and prevalence of PTHP

Study	n	GCS	Time from injury	Correlation between TBI severity and PTHP
Hadjizacharia et al 21	436	>12: 41.7% 9–12: 15.8% <9: 42.4%	Mean 1.2 days	Yes
Klose et al 20	46	>12: 47.8% 9–12: 19.6% <9: 32.6%	12 months	Yes
Klose et al 19	104	>12: 42.3% 9–12: 19.2% <9: 39.4%	Median 13 months	Yes
Bondanelli et al 17	50	>12: 32% 9–12: 14% <9: 54%	12–64 months	Yes
Kelly et al 16	22	3–15	Median 26 months	Yes
Kozlowski Moreau et al 27	55	Lowest GCS average: 8.8	>1 year	No
Schneider et al 26	70	3–15	12 months	No
Aimaretti et al 25	70	>12: 47.1% 9–12: 31.4% <9: 21.4%	12 months	No
Agha et al 23	102	9–12: 44.1% <9: 55.9%	Median 17 months	No
Lieberman et al 22	70	–	Median 13 months	No

GCS, Glasgow Coma Scale; PTHP, post-traumatic hypopituitarism; TBI, traumatic brain injury.