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. 2017 Aug 31;88(11):971–981. doi: 10.1136/jnnp-2016-315500

Types of evidence (adapted from Agency for Healthcare Policy and Research 1992) 4

Level Evidence
Ia Evidence obtained from meta-analysis of randomised controlled trials
Ib Evidence obtained from at least one randomised controlled trial
IIa Evidence obtained from at least one well-designed controlled study without randomisation
IIb Evidence obtained from at least one other type of well-designed quasi-experimental study
III Evidence obtained from well-designed non-experimental descriptive studies, such as comparative studies, correlation studies and case–control studies
IV Evidence obtained from expert committee reports or opinions and/or clinical experience of respected authorities