Table V.
Univariate and multivariate logistic regression analysis of predictors for advanced liver fibrosis in patients with positive or negative HBeAg status.
| A, HBeAg positive patients (n=138) | ||||||
|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||||
| Variables | OR | 95% CI | P-value | OR | 95% CI | P-value |
| Sex | 0.22 | 0.07–0.72 | 0.012 | 0.18 | 0.05–0.66 | 0.009 |
| Age (years) | 1.02 | 0.97–1.08 | 0.477 | |||
| ALT level | 1.11 | 0.41–2.99 | 0.846 | |||
| HBV DNA | 1.29 | 0.97–1.72 | 0.083 | 1.44 | 1.02–2.03 | 0.041 |
| BMI | 1.06 | 0.92–1.23 | 0.417 | |||
| AST levels | 6.55 | 1.44–29.84 | 0.015 | 5.31 | 1.01–27.97 | 0.049 |
| B, HBeAg negative patients (n=167) | ||||||
| Univariate analysis | Multivariate analysis | |||||
| Variables | OR | 95% CI | P-value | OR | 95% CI | P-value |
| Sex | 0.55 | 0.21–1.42 | 0.217 | |||
| Age (years) | 1.01 | 0.95–1.06 | 0.893 | |||
| ALT levels | 7.91 | 2.61–24.05 | <0.001 | 5.42 | 1.74–16.910 | 0.004 |
| HBV DNA | 1.41 | 1.05–1.89 | 0.021 | 1.42 | 1.00–2.01 | 0.05 |
| BMI | 1.07 | 0.92–1.23 | 0.378 | |||
| AST levels | 2.06 | 0.55–7.71 | 0.284 | |||
OR, odds ratio; CI, confidence intervals; ALT, alanine aminotransferase; HBV, hepatitis B virus; AST, aspartate aminotransferase; BMI, body mass index; HBeAg, hepatitis B e antigen.