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. 2017 Dec 21;14:257. doi: 10.1186/s12974-017-1035-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — IL-1β, TNF-α, IL-1ra, and TGF-β1 mRNA levels in MS patient/HC subject-derived monocytes. qPCR analysis was performed to detect a IL-1β (HC N = 9/MS N = 15), b TNF-α (HC N = 10/MS N = 13), c IL-1ra (HC N = 8/MS N = 14), and d TGF-β1 (HC N = 8/MS N = 14) mRNA levels in primary monocytes from MS patients and HC subjects. Data are shown in box-and-whiskers plots in which the median is represented by a horizontal line within the box, and the lower and upper whiskers represent the 5 and 95 percentiles. **p < 0.01. MS multiple sclerosis, HC healthy controls