Fig. 6.

Comparative analysis of the EDs for Kv, BacNav, and TRP channels, corresponding to subdivision Q = 4 (see quality scores in SI Appendix, Fig. S13). While Kv and BacNav show similar organization, coherent with their analogous functional requirements, TRP is characterized by a different domain pattern, consistent with its ligand-gated properties and loss of voltage-gated ones, specific to the other two channels.