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Number of SNO sites different at baseline
| Category | No. SNO sites | Change in dmdmdx:utrn+/− vs. WT | No. SNO sites (%) | Change in dmdmdx:utrn+/−:trpc6−/− vs. dmdmdx:utrn+/− | No. SNO sites (%) |
| SNO sites selected with stringent criteria | 98 | Hyper-SNO | 89 (91%) | Reversed by ≥30% with Trpc6 deletion | 62 (70%) |
| Increased ≥30% with Trpc6 deletion | 10 (11%) | ||||
| Unchanged | 17 | ||||
| Hypo-SNO | 9 (9%) | SNO increased with Trpc6 deletion | 7 | ||
| SNO further decreased with Trpc6 deletion | 2 |
