Table 3.
(a) No. of catheters and incidence per 1000 catheter-days | |||||
All N = 796 |
0.5% CHG N = 261 |
1.0% CHG N = 278 |
10% PVI N = 257 |
P value | |
Colonization | |||||
Number of catheters (%) | 24 (3.0%) | 5 (1.9%) | 6 (2.2%) | 13 (5.1%) | 0.07 |
Incidence per 1000 catheter-days, n (95% CI) | 5.8 (3.5–8.2) | 3.7 (0.5–6.9) | 3.9 (0.8–7.0) | 10.5 (4.8–16.3) | 0.03 |
CRBSI | |||||
Number of catheters (%) | 13 (1.6%) | 4 (1.5%) | 3 (1.1%) | 6 (2.3%) | 0.51 |
Incidence, per 1000 catheter-days, n (95% CI) | 3.2 (1.4–4.9) | 3.0 (0.1–5.8) | 2.0 (0–4.2) | 4.9 (1.0–8.8) | 0.41 |
(b) Hazard ratio for each combination of antiseptic solution | |||||
Colonization | CRBSI | ||||
HR (95% CI) | P value | HR (95% CI) | P value | ||
0.5% CHG vs. 10% PVI | 0.33 (0.12–0.95) | 0.04 | 0.63 (0.18–2.22) | 0.47 | |
1.0% CHG vs. 10% PVI | 0.35 (0.13–0.93) | 0.04 | 0.41 (0.10–1.63) | 0.20 | |
0.5% CHG vs. 1.0% CHG | 0.95 (0.29–3.13) | 0.94 | 1.54 (0.35–6.90) | 0.57 |
CHG chlorhexidine gluconate, PVI povidone-iodine, HR hazard ratio, CI confidence interval, CRBSI catheter-related bloodstream infection