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. 2017 Dec 21;15:244. doi: 10.1186/s12955-017-0806-6

Table 2.

Association between metabolic, cardiovascular, gastrointestinal, and musculoskeletal conditions with the health related quality of life among individuals ≥20 years in South Australia, 2015 (N = 2912)

% Physical component score Mental component score
Crude Adjusted Crude Adjusted
Model 1 Model 2 Model 1 Model 2
Mean difference (SE) Mean difference (SE) Mean difference (SE) Mean difference (SE) Mean difference (SE) Mean difference (SE)
Metabolic conditions
Obesity* 25.3 -5.2 (0.5)a −3.6 (0.5)a −2.3 (0.4)a −0.9 (0.4)c −0.3 (0.4) 0.0 (0.4)
Dyslipidaemia 16.9 −7.3 (0.6)a −2.5 (0.6)a −0.3 (0.6) 0.3 (0.5) 0.0 (0.4) 0.0 (0.5)
Diabetes 9.3 −7.8 (0.7)a −3.7 (0.6)a −2.2 (0.6)b −0.6 (0.6) −0.1 (0.5) −0.2 (0.5)
Cardiovascular conditions
Hypertension 22.4 −7.6 (0.6)a −2.8 (0.7)a −1.1 (0.6) 1.3 (0.4)b 0.8 (0.4) 1.0 (0.5)
Heart attack 5.2 −9.4 (1.0)a −3.7 (1.0)a −1.7 (1.2) 0.4 (0.7) −0.8 (0.7) −0.9 (0.8)
Atrial fibrillation 3.2 −8.4 (1.2)a −4.0 (1.1)a −2.7 (1.0)b 0.9 (0.9) −0.1 (0.9) 0.1 (0.9)
Angina 2.3 −12.1 (1.5)a −5.2 (1.3)a −1.7 (1.2) −1.1 (1.3) −0.4 (1.1) 0.2 (1.2)
Stroke 1.7 −13.0 (1.3)a −6.5 (1.6)a −4.2 (1.7)c −1.7 (1.5) −1.3 (1.5) −1.3 (1.5)
Heart failure 1.0 −14.9 (1.6)a −9.1 (1.6)a −6.1 (1.5)a 1.0 (1.4) −0.2 (1.3) 0.2 (1.4)
Gastrointestinal conditions
Gastroesophageal reflux 8.4 −6.1 (0.9)a −3.3 (0.7)a −1.7 (0.7)c −2.3 (0.8)b −1.1 (0.7) −0.8 (0.7)
Irritable bowel syndrome 7.9 −4.7 (0.9)a −2.9 (0.7)a −1.7 (0.7)c −3.3 (0.7)a −1.9 (0.6)b −1.7 (0.6)b
Ulcerative colitis 0.9 −5.0 (2.6) −2.2 (2.2) −0.9 (1.8) −6.0 (1.7)b −5.0 (1.7)b −4.5 (1.7)b
Crohn’s disease 0.8 −4.7 (3.1) −3.7 (2.7) −3.0 (2.5) −2.4 (2.4) −1.2 (1.8) −0.1 (1.6)
Coeliac disease 0.7 −1.7 (2.1) −1.9 (1.6) −1.7 (1.9) −0.6 (0.6) −0.1 (1.1) 0.4 (1.1)
Musculoskeletal conditions
Osteoarthritis 25.6 −10.4 (0.5)a −7.1 (0.5)a −6.1 (0.5)a −0.6 (0.5) 0.0 (0.5) 0.2 (0.5)
Gout 6.1 −5.3 (0.9)a −1.9 (0.9)c −0.1 (0.9) 0.3 (0.7) −0.9 (0.6) −0.8 (0.6)
Osteoporosis 5.2 −8.7 (0.9)a −3.1 (0.8)a −2.1 (0.7)b −1.2 (0.8) −1.4 (0.7) −1.5 (0.7)c

*Obesity was defined as having a BMI ≥ 30, based on self-reported data for weight and height

Model 1: predicted means adjusted for sex, age, marital status, area of residence, educational level, working status, socioeconomic position (Socio-Economic Indexes for Areas Index of Relative Socio-economic Advantage and Disadvantaged), fruit/vegetable consumption, physical activity, smoking status, alcohol intake, and mental health status

Model 2: predicted means adjusted for variables in model 1 + mutual adjustment between chronic conditions

Associations with a p-value a < 0.001; b < 0.01; c < 0.05

Crude R2 for PCS and MCS were: Obesity 4.8% and 0.2%; Dyslipidaemia 7.0% and 0.02%; Diabetes 4.7% and 0.04%; Hypertension 9.2% and 0.4%; Heart attack 4.0% and 0.01%; Atrial fibrillation 2.0% and 0.03%; Angina 3.1% and 0.03%; Stroke 2.6% and 0.1%; Heart failure 2.0% and 0.01%; Gastroesophageal reflux 2.7% and 0.5%; Irritable bowel syndrome 1.5% and 1.1%; Ulcerative colitis 0.2% and 0.4%; Chron’s disease 0.2% and 0.1%; Coeliac disease 0.02% and 0.01%; Osteoarthritis 19.2% and 0.1%; Gout 1.5% and 0.01%; Osteoporosis 3.5% and 0.1%. Adjusted R2 for models including just sociodemographic, lifestyle, and mental health status variables were 27.2% for PCS and 23.4% for MCS, while R2 for full models with mutual adjustment of all conditions (Model 2) were 38.1% and 24.4%, respectively